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engineer

mastery

UK /ˌɛn(d)ʒɪˈnɪə/ US /ˌɛnd͡ʒɪˈnɪ(ə)ɹ/nounverb

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What is the meaning of 'engineered' in this sentence?

In an interesting animal study, scientists engineered mice with a specific gene defect that caused memory and learning problems.