nihilism

mastery
UK /ˈnaɪ.(h)ɪ.lɪz.m̩/ US /ˈnaɪ.əˌlɪz.m̩/nounname

card 1 of 7 · synonym

Which word is closest in meaning to 'nihilism' in this sentence?

Melancholia is the most typical presentation of depression with delusions of nihilism or guilt.