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obnoxious

mastery

UK /əbˈnɒkʃəs/ US /əbˈnɑkʃəs/adj

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What is the meaning of 'obnoxious' in this sentence?

Thinke but hovv poore thou vvaſt, hovv obnoxious; / VVhom a ſmall lumpe of fleſh could poyſon thus.