annihilate

To reduce to nothing, to destroy, to eradicate.

An atom bomb can annihilate a whole city.

But eagerness in this case, as in most others, annihilated its own delight; down came the tottering height, while the disappointed builder found relief for his sorrow in anger—sorrow's best remedy after all.

To react with antimatter, producing gamma radiation and (for higher-mass reactants, especially composite particles such as protons) lighter particles (such as pions, muons, and neutrinos).

To treat as worthless, to vilify.

of all the opinions which Antiquity hath had of men in gross, those which I most willingly embrace, and whereon I take most hold, are such as most vilifie, condemne, and annihilate us.

To render null and void; to abrogate.

To cause to become zero by means of an annihilator operator