constipate

To cause constipation in, render costive.

The medication can constipate you if you’re not drinking enough water.

The long hours of travel seemed to constipate his digestion.

To constrict, contract (tissues, the body, fibres, etc.); to make firm and compact by pressing together.

To pack or crowd together.

Constipated, costive.

By […] much Sweating, the Bowels were heated, and dry'd, and rendred Constipate.