depraved

Perverted or extremely wrong in a moral sense.

a depraved killer

The driver who speeds with reckless disregard for the consequences to others but without any intent to harm the darting child may receive jail time but is often treated far differently from the depraved killer who sets out with a purposeful plan to murder the child.

Distorted out of the normal course; abnormal.

The taste and digestion are often depraved, anorexia, nausea, inappetence and vomiting supervene, the woman desires innutritious or disgusting food, such as chalk, cinders, putrescent animal food, […]

There was a constant dripping of urine from the penis, a depraved appetite and meninguria. On examination, two calculi were easily felt, and I advised the owner that an operation was all that would save his animal […]