irreversible
UK /ˌɪr.ɪˈvɜː.sə.bəl/ US /ˌɪr.ɪˈvɝ.sə.bəl/
adj 3
Definitions
adj
1
Incapable of being reversed or turned about or back; incapable of being made to run backwards.
an irreversible engine
2
Incapable of being reversed, recalled, repealed, or annulled.
an irreversible sentence or decree
Manganism has been known about since the 19th century, when miners exposed to ores containing manganese[…]began to totter, slur their speech and behave like someone inebriated. The poisoning was irreversible, and soon ended in psychosis and death.
3
Incapable of being reversed to the original state without consumption of free energy and increase of entropy.
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