it's lonely at the top
A highly successful person in a particular field will inevitably suffer from a feeling of isolation.
VERBS
be, feel, look, seem | become, get
ADV
desperately, extremely, terribly, unbearably, very
After moving to a new city, he felt extremely lonely during his first few months.
a bit, a little, pretty, rather
oddly
After moving to the city, he felt oddly lonely in a crowded room full of strangers.