tranquilize

To calm (a person or animal) or put them to sleep using a tranquilizer dart.

The escaped lion was finally tracked down, tranquilized, and safely returned to the zoo.

Miss Ratched shall line us all against the wall, where we’ll face the terrible maw of a muzzle-loading shotgun which she has loaded with Miltowns! Thorazines! Libriums! Stelazines! And with a wave of her sword, blooie! Tranquilize all of us completely out of existence.

To make (something or someone) tranquil.

1779, Frances Burney, Evelina, Dublin: Price, Corcoran et al., Volume 2, Letter 14, p. 87, […] with words of sweetest kindness and consolation, he soothed and tranquilised me.

[…] I feel my heart glow with an enthusiasm which elevates me to heaven, for nothing contributes so much to tranquillize the mind as a steady purpose,—a point on which the soul may fix its intellectual eye.

To become tranquil.

Seest thou not, that this unseasonable gravity is admitted to quell the palpitations of this unmanageable heart? But still it will go on with its boundings. I’ll try, as I ride in my chariot, to tranquillize.

To dart (a person or animal) with a sedative

The bear should go down several minutes after being tranquilized.

Moose should only be down about 15 to 20 minutes after being tranquilized.