upend

To end up; to set on end.

To tip or turn over.

When he upended the bottle of water over his sleeping sister, the lid popped off and surprised them both.

upend the box and empty the contents

To destroy, invalidate, overthrow, or defeat.

The scientific evidence upended the popular myth.

James Meredith's forced admission was a milestone in upending the old order in America's most segregated state, a kind of race relations ground zero.

To affect or upset drastically.

By the middle of March 2020, the COVID-19 pandemic upended normal life for virtually all Americans.

Coral, another company trying to upend the salon industry, obtained $4.3 million in venture funding around the same time. But Bradley Leong, the company’s chief executive and co-founder, said that because they could not get the device’s price as low as they had hoped in its current iteration, they were making it semirobotic to decrease the cost.

A hamlet in Kirtling parish, East Cambridgeshire district, Cambridgeshire, England (OS grid ref TL7058).