woe

Great sadness or distress; a misfortune causing such sadness.

Oh, woe is me!

Thus saying, from her side the fatal key, / Sad instrument of all our woe, she took.

Calamity, trouble.

And I beheld, and heard an angel flying through the midst of heaven, saying with a loud voice, Woe, woe, woe, to the inhabiters of the earth by reason of the other voices of the trumpet of the three angels, which are yet to sound!

Don't let the little woes of life harm you / Let the joy in the life you lead / Let it charm you / Let it charm you now

A curse; a malediction.

Can there be a woe or curse in all the stores of vengeance equal to the malignity of such a practice?

Woeful; sorrowful

hys clerk was wo to do þat dede

And looking vp, when as his shield he lakt, / And sword saw not, he wexed wondrous woe

An exclamation of grief.

Miranda: O woe, the day.