isolation

The state of being isolated, detached, or separated; the state of being away from other people.

She lived her final year in complete isolation, not wanting to see anybody.

The act of isolating.

The state of not having diplomatic relations with other countries (either with most or all other countries, or with specified other countries).

As of 1975, diplomatic ostracism is still imposed by the Organization of American States (OAS). The inter-American community also exercises a trade embargo against Cuba. But even within this context of hemispheric isolation, Havana’s diplomacy is strikingly contradictory.

Israel could offer to ease North Korea’s isolation with diplomatic recognition, […] ¶ […] But Washington’s strategy of increasing North Korean isolation left no room for back-channel talks with Tel Aviv, […]

The obtaining of an element from one of its compounds, or of a compound from a mixture

The separation of a patient, suffering from a contagious disease, from contact with others (compare: quarantine)

Upon returning from the field, he went into isolation for a week so as not to infect anyone with potential diseases.