stupefy

To dull the senses or capacity to think thereby reducing responsiveness; to stun.

a stupefying drug; a stupefacient

He stupefied her by means of chloroform, a general anaesthetic.

To astonish or stun, especially as a result of some distressing action.

The police's negligence and callousness continued to stupefy her.

What if I love you!—This misery / Of your dissatisfaction and misprision / Stupefies me.

To deprive a material of the ability to undergo change or movement, especially deformation.

The next is, when it is not malleable, but yet it is not fluent, but stupified^([sic]).