tweak

To pinch and pull with a sudden jerk and twist; to twitch.

to tweak the nose.

To adjust slightly; to fine-tune.

If we tweak the colors towards blue, it will look more natural.

Economics is a messy discipline: too fluid to be a science, too rigorous to be an art. Perhaps it is fitting that economists’ most-used metric, gross domestic product (GDP), is a tangle too.[…]But as a foundation for analysis it is highly subjective: it rests on difficult decisions about what counts as a territory, what counts as output and how to value it. Indeed, economists are still tweaking it.

To tease, to annoy; to get under the skin of (someone, typically so as to irritate them, or by extension to enamor, frighten, etc).

Oh, he loved to tweak people and say things like "Hiya sweetums" to me because that was not exactly de rigueur in front of a bunch of strong feminists. He had this enormous sense of humor. I never knew what he was going to say.

I know what kinds of intervals and melodies tweak people—I know how to make people's skin crawl, how to make them shiver. I can't say it works on all listeners. There are some people, such as overly trained composers and theorists ...

To abuse methamphetamines, especially crystal meth.

To exhibit extreme nervousness, evasiveness when confronted by authorities, compulsiveness, erratic motion, excitability, etc, due to or mimicking the symptoms of methamphetamine abuse.

A sharp pinch or jerk; a twist or twitch.

a tweak of the nose

A slight adjustment or modification.

He is running so many tweaks it is hard to remember how it looked originally.

Trouble; distress; tweag.

A prostitute.

Thence to Bautree, as I came there, From the bushes near the lane, there Rush'd a tweak in gesture flanting With a leering eye, and wanton: But my flesh I did subdue it Fearing lest my purse should rue it.

Methamphetamine.