disadvantage

big, considerable, distinct, grave, great, main, major, manifest, obvious, real, serious, severe

Being unable to drive puts job applicants at a considerable disadvantage in rural areas.

competitive

The smaller company faced a competitive disadvantage when competing against larger rivals for the contract.

economic, educational, financial, racial, social

Children from poor families often face educational disadvantage when they start school.

experience, have, suffer (from)

Working from home can have the disadvantage of making it harder to separate your professional and personal life.

offset, outweigh

The extra cost may offset the disadvantage of having to travel farther to work.

feel at a

She felt at a disadvantage during the job interview because she hadn't prepared properly.

place/put sb at a

Starting school a year early placed her at a disadvantage compared to her classmates.

at a ~

Students without computers are at a disadvantage when they need to do their homework online.

despite a/the ~

Despite the disadvantage of not speaking fluent Spanish, she got the job at the hotel.

to sb's ~

The new visa rules worked to the disadvantage of international students hoping to study here.

~ for

Working from home can be a real disadvantage for people who live alone.

~ in

Working from home has some disadvantages in terms of staying connected with colleagues.

~ to

Working from home has some real disadvantages to it that people don't always consider.

advantages and disadvantages

Working from home has both advantages and disadvantages that employees should consider carefully.